MX MycoTOX Profile (Mold Exposure)

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Insight into a Growing Health Threat

The MycoTOX Profile is Mosaic’s most comprehensive assessment of mycotoxins. These low molecular weight fungal (mold) compounds are increasingly described as a global health threat given their acute and chronic adverse health impacts. This urine-based assay assesses levels of 21 different mycotoxins, including metabolites of the most toxigenic: Aflatoxins, Ochratoxins, Zearalenones, and Trichothecenes. The MycoTOX Profile has been designed to support clinicians uncover mycotoxin exposure – and guide a therapeutic strategy for prevention and treatment.

What Patients Might Benefit MycoTOX

Exposure to molds can cause health concerns due to the mold spores and/or the toxic effects of mycotoxins. Exposed individuals typically display symptoms due to mold spores however the concomitant presence of mycotoxins warrants assessment due to their negative health impact from chronic exposure.

  • Headache
  • Allergic conjunctivitis (red, itchy, watery eyes)
  • Sinus congestion
  • Nasal congestion, running, and irritation
  • Sneezing
  • Sore throat
  • Coughing, shortness of breath
  • Asthma attack (in individuals with underlying reactive airway disease) 
  • Fatigue, insomnia, memory loss, trouble concentrating

Details

As part of a thorough clinical assessment of a patient’s environmental body burden, Mosaic Diagnostic’s MycoTOX Profile complements additional insights gleaned from the Organic Acids Test, GPL-TOX Profile, Heavy Metals Test, and/or Glyphosate Test.

The Toxic Effect of Mycotoxins on Organ Systems

Acute vs Chronic Exposure to Mycotoxins

Acute exposure presents symptoms that are very severe and quick to show up. Symptoms are caused by exposure to large amounts of mycotoxins in one sitting. Chronic mycotoxicosis is exposure to a low dosage of mycotoxins for an extended period which can result in cancers and other serious health consequences.   – WebMD

Toxicities from mycotoxins can potentially affect many organ systems.

Given their ubiquitous nature, mycotoxins have come under increased scrutiny as causative agents of illness in both humans and animals. While there are somewhere between 300-400 recognized mycotoxins, only a dozen groups have been labeled as the greatest health threats. Among these, Aspergillus, Fusarium, and Penicillum are the main genera responsible for mycotoxins in the human food chain.

Exposure to these environmentally ubiquitous compounds can cause disruption of cellular processes such as protein synthesis, result in mitochondrial damage as well as glutathione depletion – and as such, have been associated with numerous health concerns.

 

How the MycoTOX Profile Guides Therapeutics

The MycoTOX Profile is Mosaic Diagnostic’s comprehensive mycotoxin assessment which has been designed to provide insight into the role that these pervasive toxic compounds may be playing in individuals with suspected mold exposures. 

When considering therapeutics to address elevated levels of mycotoxins, it is important to remember the effect mycotoxins have on an individual is influenced by age, sex, presence of other underlying diseases and/or exposures, nutritional status, and length of exposure.  As with any toxic exposure identifying and removing the source of the exposure is the first line of defense.  Other therapeutic considerations to support the body with detoxification and elimination might include:

  • Body Burden
  • Detoxification Capacity
  • Antioxidants
  • Glutathione
  • Binders

Specimen Requirement

10 mL urine minimum 

Please see collection instructions for detailed instructions.